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Only suited to short-time period use. If utilized for lengthy intervals or in significant doses, tolerance and dependence might establish, and withdrawal indicators could happen if remedy is stopped abruptly.

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Intravenous or intramuscular injections in hypotensive people or Those people in shock really should be administered very carefully and crucial indicators must be monitored.[58]

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The combination of these two CNS depressants may result in Negative effects which include an unusually very low heartbeat and respiration challenges.

Accessible from pharmaceutical manufacturers over the internet; importers on the net; internet consumer community forums.

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